Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Bos taurus (bovine)) | BDBM50093799 ((R)-1-Amino-13-eth-(E)-ylidene-8,8,11-trimethyl-6-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | n/a | 0.0130 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Dissociation constant for the inhibition of fetal bovine serum acetylcholinesterase was determined.. | Bioorg Med Chem Lett 6: 259-262 (1996) Article DOI: 10.1016/0960-894X(96)00012-1 BindingDB Entry DOI: 10.7270/Q2R49R8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Bos taurus (bovine)) | BDBM50342601 (CHEMBL1255901 | Huperzine A) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | 0.000367 | 0.0155 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Dissociation constant for the inhibition of fetal bovine serum acetylcholinesterase was determined.. | Bioorg Med Chem Lett 6: 259-262 (1996) Article DOI: 10.1016/0960-894X(96)00012-1 BindingDB Entry DOI: 10.7270/Q2R49R8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...) | BDBM10620 ((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 0.0333 | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Inhibition of Torpedo californica AChE assessed as carbamylation | J Med Chem 51: 3154-70 (2008) Article DOI: 10.1021/jm701253t BindingDB Entry DOI: 10.7270/Q22Z16D4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...) | BDBM10620 ((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 0.0333 | n/a | n/a |
University of Pardubice Curated by ChEMBL | Assay Description Pseudo-irreversible inhibition of Torpedo californica AChE using acetylthiocholine as substrate by cornish bowden plot analysis | Bioorg Med Chem 24: 1560-72 (2016) Article DOI: 10.1016/j.bmc.2016.02.033 BindingDB Entry DOI: 10.7270/Q2XW4MPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Bos taurus (bovine)) | BDBM50342601 (CHEMBL1255901 | Huperzine A) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | n/a | 0.0567 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Kinetic constant for inhibition of fetal bovine serum acetylcholinesterase | Bioorg Med Chem Lett 6: 259-262 (1996) Article DOI: 10.1016/0960-894X(96)00012-1 BindingDB Entry DOI: 10.7270/Q2R49R8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Bos taurus (bovine)) | BDBM50342601 (CHEMBL1255901 | Huperzine A) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | n/a | 0.0570 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Kinetic constant for inhibition of fetal bovine serum acetylcholinesterase | Bioorg Med Chem Lett 6: 259-262 (1996) Article DOI: 10.1016/0960-894X(96)00012-1 BindingDB Entry DOI: 10.7270/Q2R49R8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Rattus norvegicus (rat)) | BDBM50490821 (2-Fluoroethyl 4-Nitrophenyl Ethylphosphonate | CHE...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 200 | n/a | n/a |
The University of Montana Curated by ChEMBL | Assay Description Inhibition of rat brain AChE by concentration-dependent inhibition assay | Bioorg Med Chem Lett 23: 2048-51 (2013) Article DOI: 10.1016/j.bmcl.2013.02.010 BindingDB Entry DOI: 10.7270/Q2VH5RSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Rattus norvegicus (rat)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 267 | n/a | n/a |
The University of Montana Curated by ChEMBL | Assay Description Inhibition of rat brain AChE by concentration-dependent inhibition assay | Bioorg Med Chem Lett 23: 2048-51 (2013) Article DOI: 10.1016/j.bmcl.2013.02.010 BindingDB Entry DOI: 10.7270/Q2VH5RSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Rattus norvegicus (rat)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 567 | n/a | n/a |
The University of Montana Curated by ChEMBL | Assay Description Inhibition of rat brain AChE by time-dependent inhibition assay | Bioorg Med Chem Lett 23: 2048-51 (2013) Article DOI: 10.1016/j.bmcl.2013.02.010 BindingDB Entry DOI: 10.7270/Q2VH5RSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Rattus norvegicus (rat)) | BDBM50490821 (2-Fluoroethyl 4-Nitrophenyl Ethylphosphonate | CHE...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 633 | n/a | n/a |
The University of Montana Curated by ChEMBL | Assay Description Inhibition of rat brain AChE by time-dependent inhibition assay | Bioorg Med Chem Lett 23: 2048-51 (2013) Article DOI: 10.1016/j.bmcl.2013.02.010 BindingDB Entry DOI: 10.7270/Q2VH5RSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Rattus norvegicus (rat)) | BDBM50490822 (2-Fluoroethyl 4-Nitrophenyl Methylphosphonate | CH...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 1.02E+3 | n/a | n/a |
The University of Montana Curated by ChEMBL | Assay Description Inhibition of rat brain AChE by concentration-dependent inhibition assay | Bioorg Med Chem Lett 23: 2048-51 (2013) Article DOI: 10.1016/j.bmcl.2013.02.010 BindingDB Entry DOI: 10.7270/Q2VH5RSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Rattus norvegicus (rat)) | BDBM50490822 (2-Fluoroethyl 4-Nitrophenyl Methylphosphonate | CH...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 1.03E+3 | n/a | n/a |
The University of Montana Curated by ChEMBL | Assay Description Inhibition of rat brain AChE by time-dependent inhibition assay | Bioorg Med Chem Lett 23: 2048-51 (2013) Article DOI: 10.1016/j.bmcl.2013.02.010 BindingDB Entry DOI: 10.7270/Q2VH5RSV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Bos taurus (bovine)) | BDBM50027343 (CHEBI:75701 | ISOPROPYL METHYLPHOSPHONOFLUORIDATE) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 1.23E+4 | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Inhibition of bovine AChE | J Med Chem 51: 3154-70 (2008) Article DOI: 10.1021/jm701253t BindingDB Entry DOI: 10.7270/Q22Z16D4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Bos taurus (bovine)) | BDBM50027342 (CHEMBL483105) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 1.10E+5 | n/a | n/a |
Universit£ di Siena Curated by ChEMBL | Assay Description Inhibition of bovine AChE | J Med Chem 51: 3154-70 (2008) Article DOI: 10.1021/jm701253t BindingDB Entry DOI: 10.7270/Q22Z16D4 | |||||||||||
More data for this Ligand-Target Pair |